
Clinical research presented at the 32nd Annual Scientific Meeting of the European Association for Osteogenesis Imaging (EAO) has highlighted the superior effectiveness of anodized implant surface technology. Ndent Investigating how this surface optimizes bone integration and protects soft tissue, even in patients with complex underlying conditions.
1. Challenges in implant restoration in difficult clinical cases
One of the biggest goals of modern dentistry is to expand the success rate of implant restorations to patients with underlying conditions or challenging clinical situations. Risk factors such as a history of periodontal disease, diabetes, smoking habits, or significant bone loss all increase the risk of rejection and directly affect the osseointegration process.
To address this problem, scientists have researched and applied implant surface optimization technology. The most notable is the gradual anodizing process – a surface design that changes roughness from the implant apex (medium roughness) to the implant neck (minimum roughness).
2. What is the gradual anodizing surface technology?
Progress anodizing It is an electrochemical treatment method that creates a thick and durable titanium oxide film on the implant surface, while also allowing for adjustment of micro-roughness and chemical structure.
With its "gradual anodizing" design, the implant surface is intelligently crafted to meet the specific biological needs of each tissue layer (Bordin et al., 2023):
- Body and tip area (moderate roughness): Accelerate the process bone integration fast and stable.
- Neck area (minimal roughness): Optimizing soft tissue adhesion creates a protective mucosal barrier, preventing bacterial growth and minimizing the risk of peri-implantitis.
(This feature is completely identical to Nobel Biocare's proprietary TiUltra surface technology).
3. Real-world data: Impressive success rate per 1000 patients

A large-scale, multicenter study (data reported by Bordin et al., 2023) collected real-world data from 1,026 patients with an average age of 53.2 years. A notable feature of this study was the inclusion of patient groups at high clinical risk (those often viewed with apprehension when considering transplantation):
- The average age of patients was 53.2 ± 11.71 years (ranging from 18 to 71 years), with females accounting for 54.91% of the total number of patients.
- 7.9% The patient uses tobacco (nicotine).
- 8.4% have a history of periodontitis and 1.6% I previously had peri-implantitis.
- 4.4% They have parafunctional habits (such as teeth grinding).
- 2.2% I have diabetes.
- 5.9% having other serious medical conditions (osteoporosis, currently using bisphosphonates, or having had cancers outside the oral cavity).
- 25.3% The number of implant sites requiring simultaneous Bone-Guided Grafting (GBR) is significant.
Amazing results
In total 1,564 dental implants Of the 1,002 patients who received actual treatment, only a few were transplanted. 35 failed cases during a follow-up period ranging from 0 to 42.8 months (Bordin et al., 2023).
This means the implant survival rate has reached a certain level. ~97.7%. This is clear evidence that the implant has undergone surface treatment. anodizing provide the possibility bone integration Extremely robust, despite the disadvantages in the patient's physiological background or the need for simultaneous bone grafting.
4. Clinical Significance for Dentists

Data from over 1000 patients has reinforced the confidence of dentists in choosing implants with a specific surface finish. anodize.
- Ensure optimal bone integration: The electrochemically treated surface stimulates bone-forming cells to become more active, shortening the healing time.
- Perfect soft tissue response: The neck of the implant is uniquely designed to allow connective tissue to adhere tightly, creating a "biological barrier" that protects the underlying alveolar bone.
- Expanding the indications for treatment: This helps dentists confidently perform prosthetic restorations for patients with a history of periodontal disease, smoking, or requiring complex bone grafting, while maintaining a long-term success rate.
5. References
Bordin, S.K., Lemos, CAA, Palla, G., Chagas, E., R., P., M., J., B., R., CAA, P., G., & E., C. (2023). Osseointegration and soft tissue response to gradually anodized surface implants: Real-world data from a 1000-patient study including revealing compromised subpopulations. Foundation for Oral Rehabilitation (FOR). Report presented at the 32nd Annual Meeting of the European Osteogenesis Association (EAO), Berlin, Germany.
Nobel Biocare – A global pioneering brand in premium implant solutions featuring surface technology. anodizing The world's most advanced (TiUnite, TiUltra). Contact Ndent now for consultation.



